Researchers from the CDC, US and Brazil found that congenital Zika syndrome was uniquely characterized by five birth defects: severe microcephaly with partially collapsed skull; decreased brain tissue with subcortical calcifications; extreme muscle tone; eye damage with macular scarring and increased pigmentation; and limited joint motion range. The findings in JAMA Pediatrics were based on a review of 34 studies on the clinical features of CZS.
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